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Preclinical studies show minimal toxicity in research models, though some reports note temporary fatigue, nausea, or mild injection-site irritation

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Illustratively, it is produced in the central nervous system (i.e., brainstems raphe nuclei) (12% of the serotonin in the human body), skin (i.e., Merkel cells), lung (pulmonary neuroendocrine cells), gastrointestinal tract (90% of the serotonin in the human body) (i.e., enterochromaffin cells), and rest of 8% is stored in platelets [166]