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Thiamine transport is also significantly reduced by bacterial lipopolysaccharide and in sepsis (163, 164)

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C.VucicD.et al (2014)

Still, progress is being made in clarifying the modern epidemiology of TD, the neural circuitry involved, and the contribution of dopamine signaling confirmed by newer effective vesicular monoamine transporter type 2 (VMAT2) function inhibitors, which rekindled the interest about TD and enriched a practical management algorithm for the condition

Pires-Lapa MA, Tamura EK, Salustiano EM, Markus RP

If the metabolic pathways supplying GSH cannot maintain specific levels in the presence of highly expressed PCS, the consumption of GSH usually leads to changes in the GSH/GSSG ratio that exacerbate oxidative stress [62, 72]