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Description
Considering tumors as relatively homogeneous entities exclusively composed of malignant cells and attributing CDDP resistance only to cancer cell-intrinsic mechanisms (hence neglecting the prominent structural and functional impact of stromal and immune cells) appears indeed as an excessive oversimplification (see below), and may in part explain why clinically applicable strategies for restoring CDDP sensitivity are still missing

Studies have explored its potential in models of ulceration, inflammatory bowel disease analogues, and intestinal fistulas

Boosting NAD + blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes
All patients included in this trial had painful neuropathic symptoms consistent with SFNSL that were unresponsive to the standard therapies for chronic sarcoidosis

Competitive Landscape 2.3

Whether its genetic pigmentation, long screen hours, poor sleep, stress, or harsh sun exposure, under-eye darkness can make the face look tired, aged, and dull even when the skin is otherwise healthy
