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In animal ulcer models, it preserves mucosal integrity and reduces lesion size by modulating inflammatory pathways

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Turnover of renal GSH suggests that a further 2 1-( N , N -dimethylamino)diazen-1-ium-1,2-diolate (PABA/NO) inhibits SERCA, perhaps, at the same site as thapsigargin initiating intracellular Ca 2+ increase, activating CaM and consequently eNOS with the resultant NO burst