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ZhangSWangCSunYWangGChenHLiDet al

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T1 was further associated with a nonsignificant increase in thymic output (sjTREC), remodelling of T-cell subsets, and reduced T-cell exhaustion (lower PD-1), whereas TIM-3 remained unchanged [96]

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Metabolomic analysis We used Biocrates AbsoluteIDQ p180 kit to analyze cardiac metabolites from female mice [Young ( n = 7), Old Con ( n = 8), and Old mAb ( n = 7)] with UPLC-MS/MS Xevo TQ, Waters, Pittsburgh, PA, USA) in the Einstein Stable Isotope and Metabolomics Core, according to the manufacturers instructions (BIOCRATES Life Sciences AG, Innsbruck, Austria)

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By contrast, CP R77A/T79A/D80A/K87A -HA and CP R122A -HA were co-immunoprecipitated with OsVIRK1-GFP, like WT CP-HA (Supplementary Fig

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Hit gene selection The gene hits were selected according to the following criteria

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This same model can be translated to a growing mass of tumor cells whereby ADCC acts to wipe out a growing malignancy (56)

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