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We first examined the concentration-dependent effect of PFOS on mitochondrial bioenergetics and discovered that an increase in the PFOS concentration from 100 to 200 M significantly decreased mitochondrial bioenergetics, as evidenced by the decreased ATP production, maximal respiration and spare respiratory capacity, and increased proton leakage (Fig

[DOI] [PubMed] [Google Scholar] 35.Richard P.O., Fleshner N.E., Bhatt J.R., Hersey K.M., Chahin R., Alibhai S.M

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Possible Role of TMAO in Promoting AS Below, we discuss the TMAO-involved mechanisms of AS from the perspectives of immunity, inflammation, cholesterol metabolism, and atherothrombosis ( Figure 1 )