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Proc Natl Acad Sci USA 95:1573015734 Betz H, Harvey RJ, Schloss P (2001) Structures, diversity and pharmacology of glycine receptors and transporters

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Intriguingly, our biophysical studies suggest that Syn S129E exhibits increased promiscuous, nonfunctional interactions compared to Syn WT , albeit to a lesser extent than Syn 1103