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Clinical trials are necessary to determine the appropriate dosage for humans
Bpy is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center
This authorization is based on safety and effectiveness data in this age group and adults
2018;13:e0208584
Interestingly, copper accumulation in ATP7B -deficient hepatic cells increases the expression of PRNP through the transcription factor MTF1 [61,62,63], thus forming a positive feedback loop that amplifies copper overload under the pathological condition
