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The sleep deprivation pro-atherogenic effect in animal model of sleep fragmentation is mediated, at least in part, by reduced hypothalamic release of hypocretin (i.e., orexin), a wake-inducing neuropeptide, which limits the production of leukocytes (monocytes and neutrophils) and atherosclerosis development, and has been inversely associated with the risk of myocardial infarction, heart failure, and obesity 205

According to the World Health Organization (WHO), a normal sperm concentration is around 15 million sperm per milliliter (mL) of semen

However, as elucidated by Ecker [132], it is important to note that the neuroanatomical differences are neither unique to nor necessarily causal for ASD