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This lipid peroxidation impairs their phagocytic function mediated by TLR2, preventing them from effectively clearing tumor cells that have undergone ferroptosis, ultimately resulting in tumor resistance to ferroptosis therapy (152)
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Sathibabu Uddandrao, Chandrasekaran Ponnusamy, Saravanan Ganapathy, Sethumathi Ponnusamy Pudhupalayam, Sengottuvelu Singaravel, Ponmurugan Ponnusamy, Jagadeesan Ramasamy, Kalaivani Aiyasamy, Vadivukkarasi Sasikumar Revista Brasileira de Farmacognosia .2023
38 Second, intestinal DAF-16 is required for the lifespan extension induced by neuronal HSF-1 overexpression
