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doi: 10.1101/cshperspect.a020453 17 BesussoD.SchellinoR.BoidoM.BelloliS.ParolisiR.ConfortiP.et al

Conclusion Although the therapeutic potential for BPC-157 shows promise in animal models, gaps in validated pharmacokinetic and safety methods remain barriers to optimal drug development

Studies show that iron-sag markers can be traced in cellular and animal models of neurodegenerative diseases ( in vitro assay, ferroptosis is associated with reduced expression of SLC7A11 and GPX4 proteins, as well as ROS accumulation in corticosterone-constructed hippocampal progenitor neurons (Li E

Thus, iron is an indispensable factor in the redox system

The peptide also tolerates lyophilisation and reconstitution without measurable loss of activity, and stable storage at -20C exceeds 24 months in published shelf-life data