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Hu Z, Zhang H, Yang SK, Wu X, He D, Cao K, Zhang W (2019) Emerging role of ferroptosis in acute kidney injury

: 2027 - 2028

When you add a diluent, you're reawakening the molecule, but you're also making it vulnerable

We synthesize advances (20152025) across principal generatorsmitochondrial electron transport, NADPH oxidases, xanthine oxidoreductase and ER/peroxisomal oxidoreductasesto show how compartmental H 2 O 2 microgradients encode reversible cysteine signaling, while iron-rich niches pivot chemistry toward peroxynitrite, Fenton-derived OH, lipid peroxidation and regulated cell death (apoptosis, ferroptosis, parthanatos)

To treat chemotherapy extravasations (chemotherapy that has leaked and become trapped in surrounding tissue): DMSO may be used to treat this condition in a hospital setting