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Anti-tumour efficacy was compared to the anti-EGFR antibody cetuximab to exclude any EGFR blockade effects on tumour growth inhibition 25 and determine the ability of a bispecific format to inhibit BRAF -mutated tumours by EGFR-specific T-cell activation

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One of the most significant changes was increased DNA methylation in an intron of the disks large homolog 4 ( Dlg4 ) gene

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