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doi: 10.1016/0306-9877(95)90512-X
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Aging cell 19, e13235
Mathias et al
In their studies, structural modifications were made to replace the piperazine sulfonamide part of sildenafil and vardenafil with groups that have a terminal zinc binding group ZBG (a hydroxamic acid or an ortho-aminoanilide moiety), which is essential for HDAC inhibition
Diosmin mitigates gentamicin-induced nephrotoxicity in rats: Insights on miR-21 and-155 expression, Nrf2/HO-1 and p38-MAPK/NF-B pathways
