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While the first studies showing this were in mice [14], human studies have corroborated these findings [200], although its importance in relationship to traditional clearance pathways across the BBB and subarachnoidal granulations has been challenging to quantify
Guo J, Yan E, He L, Wang Y, Xiang Y, Zhang P, et al
The observed differential mRNA and protein expression levels of GPX4 and TfR1 in vitro may bear clinical relevance when considering factors such as tumor heterogeneity and the wide-ranging therapeutic response of thyroid tumors harboring diverse mutational signatures
K., & Pratap, K
