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A double-blind, placebo-controlled trial in 95 patients with irritable bowel syndrome or inflammatory bowel disease and normal B12 levels found no significant improvements in fatigue, although B12 levels increased in the B12 group who received 1000 g per day per os (p.o.) for 8 weeks (form not reported)

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Unopened bacteriostatic water is generally stored at 1525C (5977F) in a clean, dry environment away from direct sunlight and freezing conditions