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Immune exosomes loading self-assembled nanomicelles traverse the blood-brain barrier for chemo-immunotherapy against glioblastoma
Upon dsDNA binding, cGAS catalyzes the synthesis of the second messenger cyclic GMPAMP (cGAMP), which uniquely contains a mixed 25 and 35 phosphodiester linkage conferring high stability and potent signaling capacity [97]
Tumors exceeding 12 mm in diameter require neovascularization to overcome diffusion-limited nutrient supply
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TCM consists of numerous components
