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National Geographic magazine
Autophagy can degrade iron storage proteins in cells, leading to excessive release of free iron and accumulation of ROS, thereby acti-vating the process of ferroptosis (12)
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Previous studies reported that ferroptosis induced neutrophil migration and adhesion to the vascular endothelial cells by TLR4/Trif/type I IFN-dependent signaling pathway, in turn leading to heart transplantation-related injury (78)
Cystine taken by itself is poorly absorbed
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