nucleic glutathione liposome Liposomes: An emerging carrier for targeting Alzheimer's and Parkinson's diseases: Heliyon Liposomes: structure, composition, types, and
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Physiol Rev 99(2):10471078 Cao DW, Jiang CM, Wan C, Zhang M, Zhang QY, Zhao M, Yang B, Zhu DL, Han X (2018a) Upregulation of MiR-126 delays the senescence of human glomerular mesangial cells induced by high glucose via telomere-p53-p21-Rb signaling pathway

For instance, in AD mice, mitochondrial damage increases mtDNA leakage into the cytosol, where it engages cGAS and activates STING, driving microglial secretion of type I interferons and pro-inflammatory cytokines that contribute to neuronal dysfunction [93]

Furthermore, the effective discrimination of AD and non-demented controls based on multiple CpG sites and RNA expression underscores the potential of DNA methylation patterns as biomarkers for AD diagnosis and prognosis (175)

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In terms of molecular function, cluster A is primarily associated with ribosomal structural components, whereas cluster B is related to the regulation of transmembrane transporter activity (Figure 5D
