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[30] concluded that Mucuna pruriens has therapeutic potential for neurodegenerative diseases, especially PD

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The ER stress regulator Bip mediates cadmium-induced autophagy and neuronal senescence

493 Cell senescence can be accelerated when various organelles meet overloaded stress or proteotoxicity, such as misfolding of nuclear, ribosomal, peroxisomal, and mitochondrial proteins, 494,495,496,497 leading to aberrant protein aggregates that dampen the cross talk of organelles