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Lipofuscin, also called age pigment, is often considered a symbol of aging

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Iron overload decreases CaV13-dependent L-type Ca2+ currents leading to bradycardia, altered electrical conduction, and atrial fibrillation

We also evaluated the mRNA expression of the ET transporter, OCTN1, in the liver after 1 and 28 days administration, and found that OCTN1 expression was reduced after a single dose of ET++ (Fig

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