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Upon establishment of balanced ratios between sgRNA-transduced (IRFP670-positive) and non-transduced cells, cultures were treated with low concentrations of Venetoclax that did not interfere with the proliferation of MOLM-13 cells (1 nM

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Research indicates that uterine fibroid tissue exhibits abnormally high expression of CYP1B1, an enzyme responsible for hydroxylating E into the highly active metabolite 4-hydroxyestradiol (4-OH-E)

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It contains 0.9% benzyl alcohol, which stops bacterial growth within the vial, allowing for multiple uses from the same vial