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Glycosylation at N297 stabilizes the antibody structure while enhancing ADCC and CDC, both of which contribute to immune-mediated tumor clearance

This GSH down modulation was followed by change in cytokine profile

As a potent triple monoamine reuptake inhibitor (MRI), Tesofensine is a premier tool for investigating the simultaneous modulation of dopamine, norepinephrine, and serotonin pathways

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These latter processes contribute to the neuronal inflammation response a key factor in neurodegenerative diseases including AD [34-36]

Hippocampal neurons were obtained from Wistar rat embryonic brains and plated on 6 well glass bottom plates coated with 0.01% poly-L-Lysine (Sigma-Aldrich) and 0.1 mg/mL laminin (ThermoFisher Scientific)