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The risk with larger vials is greater financial loss if reconstitution goes wrong, so these are best reserved for researchers who have already mastered the technique on standard 5mg or 10mg vials
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67 68 Long term epidemiological studies also indicate that treatment with pharmacological B 12 doses and the corresponding increase in serum B 12 do not increase mortality
This procedure is performed utilizing imaging techniques like ultrasound and x-ray to ensure accurate needle placement
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