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Recombinant ICs can also be generated by fusing antigens with the Fc fragment of IgG into one molecule and expressing the construct in appropriate vectors

During the 1990s and early 2000s, research interest increased in peptide fragments capable of interacting with cellular signalling systems and molecular regulatory pathways

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However, noticeable effects like improved sleep typically appear within 1-2 weeks, while body composition changes usually become apparent around weeks 6-8

9 However, mounting genetic analyses, post-mortem studies, and functional assays have begun to shed light on mitochondria as a promising therapeutic avenue