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It appears in the peptide research space because its mechanism NNMT inhibition affecting NAD+ and SAM pathways intersects with the same metabolic systems that peptide researchers study

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ASSESSMENT OF VITAMIN B12 STATUS: USEFULNESS AND LIMITATIONS OF BIOMARKERS The total serum vitamin B12 (cobalamin) level is frequently insufficient as a standalone marker to accurately evaluate vitamin B12 status

B12 supplements often don't help and may even hurt people with sickle cell anemia, Wright says
