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Inhaled (nebulized or aerosolized) reduced GSH to augment the deficient GSH levels of the lower respiratory tract has been used effectively in numerous pulmonary diseases and respiratory conditions like HIV seropositive individuals, cystic fibrosis and idiopathic pulmonary fibrosis, among others (131133)

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Unlike the traditional approach whereby data are obtained from individuals deemed healthy, these investigators applied an indirect method designed to overcome the ethical and resourcing difficulties experienced when sampling apparently healthy individuals

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