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The synthesis of GCL, along with other targets involved in the antioxidant response, is under the control of the transcription factor, Nrf2 (Baird and Dinkova-Kostova 2011)

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In addition, ROS may amplify the inflammation process by gene involved in the inflammatory response, particularly via activation of the nuclear transcription factor NF-k, which in turn up regulates pro-inflammatory cytokines and leukocyte adhesion molecules

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Its a process that brings increased blood flow and heightens defenses around an area that is damaged

doi: 10.3389/fphar.2016.00385 31 WangMGuoZWangS