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[DOI] [PubMed] [Google Scholar] 108.Schfer F.Q., Buettner G.R

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doi: 10.1016/j.plipres.2019.04.002 19 BujakA

The first crystal structure of human SQOR was reported in 2019 by 5 -fold faster than that to the disulfide within the enzyme ( k cat / K m of SQOR toward H 2 S was estimated to be of the order of 10 7 M -1 s -1 ( 7 -fold higher than the rate constant for sulfide addition to disulfide in solution at pH 7.4 and 25 C (0.6 M -1 s -1 ) ( In the proposed catalytic cycle, sulfide first attacks the trisulfide bridge of the enzyme, generating persulfides at both Cys201 and Cys379

C., Ruiz, J
