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E., Gerson, S
Similarly, Lu AA21279, another GlyT1 inhibitor, demonstrated a positive effect in the MEST test at doses of 3.030 mg/kg (p.o.) (Kalinichev et al
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Preclinical toxicological data: Acute and subacute toxicity studies in rats did not reveal any mortality or significant organ toxicity, even at doses well above therapeutic doses (up to 100 times the effective dose)
