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Targeting astrocyte-mediated glutamate transport (e.g., enhancing GLT-1 function) or lactate shuttling (e.g., activating MCT1/2 transporters) represents a promising therapeutic strategy to preserve neuronal bioenergetics and slow disease progression (Yang et al., 2024)

Liu Y, Liu F, Iqbal K, Grundke-Iqbal I, Gong CX

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Overall, the findings from the current literature are conflicting and inconclusive, although they raise some important questions about whether certain diet-based factors, including diets with a high UPF exposure, may contribute to and influence neurodevelopmental outcomes across both healthy development and in the case of ASD

Elevated glutathione levels have also been reported in bipolar disorder [28] and following alcohol consumption [47] where a link between affective behavior and oxidative stress was also observed