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Metabolic bioactivation as a pathogenic mechanism

This work was supported in part by funding from the NIH and the University of Hawaii Foundation

Reduced antioxidant enzyme activity in ME/CFS Research has revealed that the activity of key antioxidant enzymes including superoxide dismutase (SOD), catalase (CAT), and GSH peroxidase (GPx) is attenuated in ME/CFS patients, which consequently aggravates oxidative stress

Severe and persistent bronchial inflammation and chronic bacterial infection, along with airway mucus obstruction, are hallmarks of CF lung disease and participate in its progression

The preclinical and clinical use of NAC This literature review summarizes research results concerning the efficacy of NAC in SUD
