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Omeprazole and pantoprazole: These acid reducing drugs can impair the absorption of vitamin B12 in humans with long-term use

Considering previous findings emphasising the relationship between this type of motor function and neural inhibition/GABA, this effect could also be explained by Vitamin-B6 increasing GABAergic tone in the brain

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These inflammatory mediators induce oxidative stress, compromise the nerves protective barriers, and provoke myelin degradation, thereby accelerating axonal damage and degeneration 7