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Description
C.SpectorA.WongG
In cross section, the eosinophil contains approximately 30 of these membrane-bound, core-containing, secondary granules.1 Five highly basic proteins are found within the granules: (1) major basic protein (MBP)-1, (2) MBP-2, (3) eosinophil-derived neurotoxin (EDN) also known as ribonuclease (RNase)2, (4) eosinophil cationic protein (ECP) also known as RNase3, and (5) eosinophil peroxidase (EPO)
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10.1097/MD.0000000000014244 63 ZhangL.ZhangL.LiF.LiuW.TaiZ.YangJ.et al
We conclude that decreased GSH and increased iron in tandem in the SN provide an early diagnostic biomarker for PD
The Michael adduct of HNE to Cys on proteins causes considerable changes in conformations of the proteins (12)
