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Variations in genes, pathological function of Cortico-Striato-Thalamo-Cortical (CSTC) circuits and dysregulation in the synaptic conduction have been the major factors involved in the pathological progression of OCD
The peptides administration has been linked to the release of serotonin in brain regions associated with mood and motor control, suggesting a bidirectional communication pathway between the gut and the brain
The control group did not receive the peptide dose, receiving saline instead
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