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Adaptation to chronic-cycling hypoxia renders cancer cells resistant to MTH1-inhibitor treatment which can Be counteracted by glutathione depletion

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Neuregulin-1, a Schwann cell growth factor secreted by nerve cells, 95 binds to its receptorsEGFR and HER2on Schwann cells to mediate cell growth and migration

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References Stockwell BR, Angeli JPF, Bayir H, Bush AI, Conrad M, Dixon SJ et al (2017) Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease