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doi: 10.3390/nu12092546

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In an in vivo study, a quercetin metabolite (4,5-diacetyl-3,Y,7-trimethyl-quercetin), administered orally BID for 4 days protected mice against lethal infection by Coxsackie virus, promoting survival in a dose-response scale: 10, 20, and 40 mg/kg increased survival by 30, 40, and 50%, respectively ( in vitro ( Inhibition of Reverse Transcriptase Quercetin has been investigated in vitro as an antiviral agent for HIV due to its ability to inhibit crucial enzymes: reverse transcriptase (RT), integrase (IN), and protease (PR) (80)

Antitumor drugs can be delivered to the tumor microenvironment when they are incorporated inside biodegradable polymeric nanoparticles, which have been explored as a novel drug delivery system in clinical trials (Park et al., 2009)

Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimers disease