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Although detection of RNA is considered not to be enough to conclude vertical transmission, a systematic review of the current literature aimed to evaluate the possibility of vertical transmission based on early RNA detection of SARS-CoV-2 after birth, and concluded that vertical transmission of the virus is very rare as observed in a minority of pregnant women tested positive for SARS-CoV-2 during the third trimester, with rates of infection similar to those of other pathogens causing congenital infections [16], [17]

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This triggers widespread inflammation, with trauma-induced mitochondrial DAMPs further intensifying oxidative stress and contributing to a sepsis-like state [22,25,26,27]