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The second hTrx1 molecule was generated by application of the twofold rotation of the TrxR dimer, and subsequent rigid-body refinement

Mechanistic and Pathway Context NNMT is involved in cellular nicotinamide processing and methylation reactions

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These results point to the interconnection between glycolysis (the central metabolic pathway in erythrocytes), energy metabolism, and cation channel-driven eryptosis

Remarkably, PDA-CQD/RBC could improve cognitive function and behavioral performance in mouse models, suggesting potent neuroprotective effects
