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In France, treatment involves the administration of 1,000 g (1 mg) of cyanocobalamin per day for 1 week, followed by 1,000 g (1 mg) per week for 1 month, followed by 1,000 g (1 mg) per month, again, normally for the remainder of the patients lifetime [10]

Eur Respir J 46:10331045 Griffin JE, Gawronski JD, DeJesus MA, Ioerger TR, Akerley BJ, Sassetti CM (2011) High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism

Obesity 31 , 111122 (2023)

Synthesis of methionine from homocysteine

If someone has a diagnosed deficiency, especially due to absorption issues, their provider might start them on weekly injections

This could be due to racial differences in B12 metabolism, or in environmental factors, most obviously diet (B12 intake)