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A population-average curve obtained by taking the mean , and across diabetic patients (bold curve in Figure 3) reveals quantal characteristics of the average GSH response to glucose: Hyperglycemia is associated with a shallow low-glutathione phase

doi: 10.1093/eurheartj/ehn170

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Elevated cortisol levels from stress can lead to skin sensitivity, breakouts, and inflammation, which often result in post-inflammatory hyperpigmentation (PIH)
