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Also, partial deficiency of the mitochondrial superoxide dismutase isoform manganese superoxide dismutase was associated with increased blood pressure in aging mice

In hereditary spherocytosis, structural abnormalities intensify oxidative damage and disrupt lipid structure, accelerating splenic elimination (50)

Such cells have evolved an array of antioxidant mechanisms, such as the thiol system, to combat oxidative stress, including nitric oxide, carbon monoxide, and hydrogen (per)sulfide [27]

doi: 10.1126/scitranslmed.aan4220

ALS is intricately linked to systemic lipid metabolic disturbances

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