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Key takeaways: ME/CFS is a multi-system disease, not just fatigue, with some being unable to work, housebound, or bedridden

Changes in the blood concentrations of specific acylcarnitines in subjects with either subjective memory complaints, mild cognitive impairment, or Alzheimer's disease, compared to cognitively healthy peers may reflect changes in the transport of fatty acids into the mitochondria and/or impairments in energy production

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Building on this, its role as a metabolic booster alongside lifestyle interventions, or sequentially with GLP-1 receptor agonists to prevent hepatic fat re-accumulation, warrants further investigation