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doi: 10.1371/journal.pone.0217111

The FOXO3a protein level is downregulated in cetuximab-resistant CRC cell lines Next, we investigated how KRAS/BRAF mutations affect FOXO3a activity and how FOXO3a is regulated in CRC cells with acquired cetuximab resistance

Principle: The technique separates components of a mixture based on their chemical properties as they are pumped through a column packed with a stationary phase
Im et al, 2011
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