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However, outcomes depend heavily on dosage, treatment frequency, and patient metabolism

It has been implicated in physiological killing of tumor cells but also in the pathogenesis of different diseases with high socio-economic impact including neurodegeneration (Stockwell 2022

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Nonaka N, Hileman SM, Shioda S, Vo TQ, Banks WA

Drug Discovery Today , Volume 00, Number 00, April 2016 Chapter 29: Challenges in the Development and Manufacturing of AntibodyDrug Conjugates ,489-497 Advances and Limitations of Antibody Drug Conjugates for Cancer