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doi: 10.1016/j.biopha.2018.07.100

conjugated miR-21-5p with a CPP (CPP YARA) for cargo loading, resulting in an 18.6-fold increase in cargo loading capacity

However, manufacturers marketing AOD-9604 as a supplement cannot make disease or therapeutic claims (e.g., "for weight loss" or "for treating obesity") without violating FDA regulations

[235] but, based upon the clinical use of carbonic anhydrase inhibitors, carbonic anhydrase activation in other tissues may be associated with adverse effects, such as ocular activation exacerbating glaucoma

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