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Cryotolerance of oocytes does not only depend on their quality, but also on the conditions provided during vitrification and warming processes

In acidic endosomes, Fe 3+ is reduced to Fe 2+ by six-transmembrane epithelial antigens of the prostate 3 (STEAP3), and transported to the cytoplasm through divalent metal transporter 1 (DMT1)

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335,336,337,338 As for non-malignant endothelial cells at regular oxygen concentrations, lactate activates hypoxia-inducible factor 1 (HIF-1) that enhance s basic fibroblast growth factor (bFGF) and vascular endothelial growth factor receptor 2 (VEGFR2) expression, which synergizes with lactate-induced VEGF secretion

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The mechanisms of enhanced desensitization and - arrestin2-dependent impairment of recovery during chronic morphine treatment in vivo are still not known