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In this form, iron can be stored in ferritin, or exported from the cell via ferroportin (FPN1) (Hou et al., 2016)

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While surveying the literature in preparation of this manuscript we have also noticed and reported an increasing interest in the role that GSTs play in neurodegeneration, where isozymes belonging to the family may be either up-regulated, mutated or absent, according to the different diseases

7 Binge drinking is classified as 4 or more alcoholic drinks for females or 5 or more alcoholic drinks for males on the same occasion (within a couple of hours of each other) on at least 1 day in the past month

Furthermore, the Sod1 G86R mouse models were developed, which express the missense mutation Gly86 to Arg of the murine SOD1 enzyme (Ripps et al., 1995), reported in the corresponding amino acid residue (position 85) of some fALS patients (Rosen et al., 1993)

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