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12,460462 Classical I FINs are identified through the depletion of GSH to trigger ferroptosis, such as erastin, its derivatives imidazole ketone erastin (IKE), 460,463,464 and cyst(e)inase, which depletes GSH by degrading cysteine and cystine

doi: 10.1016/j.biomaterials.2014.05.053 75 ChenZShiTZhangLZhuPDengMHuangCet al

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The synthesis of homocystine, cystathionine, and cystine by cultured diploid and heteroploid human cells

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