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Tomita K, Smith PM, Takayama M, Pan C, Shen SE, Wang X, Wang XS, Williams LA, Arvide EM, To C, Rajaram R, Mitchell KG, Rice DC , Hofstetter WL, Antonoff MB, Mehran RJ, Vaporciyan AJ, Walsh GL, Maxwell JE, Snyder RA, Kim MP, Tzeng CD, Mansfield PF, Swisher SG, Lee JE, Badgwell BD, Katz MHG, Ikoma N
f , Sunburst plot of differentially expressed genes belonging to biological process functional terms computed with SynGO

doi: 10.1124/mol.65.3.550

These enhance the cleavage of caspase-3 and PARP, thereby promoting apoptosis in cancer cells

For example, GSTs inactivate the 8,9-epoxide formed by the CYP450-catalyzed oxidation of the environmental toxicant/carcinogen aflatoxin B1, Figure 3a
UK dispatch from Vanta Labs
